Structure of PDB 6ki6 Chain B

Receptor sequence
>6ki6B (length=52) Species: 9606 (Homo sapiens) [Search protein sequence]
DTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKT
HG
3D structure
PDB6ki6 Structural insights into the recognition of gamma-globin gene promoter by BCL11A.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B N753 S755 S783 N12 S14 S42 PDBbind-CN: Kd=72nM
BS02 dna B K749 N756 H760 Y777 Q781 K784 R787 H788 T791 K8 N15 H19 Y36 Q40 K43 R46 H47 T50 PDBbind-CN: Kd=72nM
BS03 ZN B C744 H760 H764 C3 H19 H23
External links
PDB RCSB:6ki6, PDBe:6ki6, PDBj:6ki6
PDBsum6ki6
PubMed31467406
UniProtQ9H165|BC11A_HUMAN B-cell lymphoma/leukemia 11A (Gene Name=BCL11A)

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