Structure of PDB 6kf9 Chain B

Receptor sequence
>6kf9B (length=1114) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence]
EPTLTPDELWLVMESYWKEKGFVRQHLDSYNAFIDHGLQDVVNEFGEVVP
DIPNFKVKFGKIRIGQPEFQEAQGQRRPLYPMDARIRNLTYSAPLYLEMI
PVVNGIEQEPVEVRIGELPIMLKSKACRLYGLSDEELIKLGEDPKDPGGY
FIINGSERVIVSIEDLAPNKTLVERDERQNKVVAKVFSYRHGYRALITVE
RKKDGILYVTIPNVPKPVKFVYVMRALGLLTDKEIVEAVSDDPRIQQVLF
DNLEDASDISTQEEALDYIGRLALPGQPKEYRLRRAEHIIDNNLLPHMGV
DPENRRAKAYYLGMMALKVLELSLGLRGEDDKDHYANKRLKLAGDLLKDL
FRVAFGQLVKDMQYQMTKTYQRKGERYTFENIQRFVRNSIRPDVLSERIE
HALATGSWPGGRTGVSQLLDRTNYMSTLSHLRRVTSPLSRDQPHFEARDL
HGTHWGRICPTETPEGPNCGLVKNLALMSQITTGIPEREVREYLMKMGVV
PIEERRPAPGLYRVYLNGVLIGTVEDGRKLVERIRADRRAGKISDVINVA
LYEDEEVKEVYINSDDGRVRRPLIVVENGKPKLTREHVEGIKNGTLTWSD
LIRMGVIEYLDAEEEENAYVATWPWEVTEEHTHLELMPAAILGIPASLVP
YPEHNAAPRNTYGAGMAKQSLGLGWANFRIRVDTRGHLMHYPQVPLVNSR
IMKAVGFEDRPAGQNFVVAVLSYHGYNMEDAVIINKASIERGLARSTFFR
TYEAEEKRYLGGQKDNFEVPSPNIQGYLGEKYYRHLDEDGLIFPESKVEG
KDVLVGRTSPPRFIEEQSSLGSMVLQGRRETSVTVRPSEKGVVDKVIVTE
TGDGTKLVKVTVRDLRIPELGDKFASRHGQKGVIGLIVPQEDMPWTESGI
VPDLIVNPHGIPSRMTVGQLIEAIGGKVASLTGRRVDGTAFIGEPEEKLR
KELEELGFKHSGREIMYDGITGRRLEADIFIGVIYYQRLHHMVADKMHAR
SRGPVQVLTKQPTEGRAREGGLRFGEMERDVLIGHGAAMLLIERLLEESD
KTEVWVCESCGHLALEDKRRGKVYCPVCGEDERISKVEMSYAFKLLLDEL
KAMVIRPSLRLKDR
3D structure
PDB6kf9 Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
ChainB
Resolution3.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B E1022 G1023 R1031 E1014 G1015 R1023
BS02 ZN B C1065 C1068 C1057 C1060
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6kf9, PDBe:6kf9, PDBj:6kf9
PDBsum6kf9
PubMed33257704
UniProtQ5JE32

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