Structure of PDB 6jz3 Chain B

Receptor sequence
>6jz3B (length=578) Species: 33038 (Mediterraneibacter gnavus) [Search protein sequence]
LEYSELYPIQNEYRMMQSLDGMWKFQFDPEEIGKKSGWENGLPAPVSMPV
PSSFADFFTDHKERDYCGDFWYETEFYLPAEWRNKKIWLRFGSITHRGTV
YCNGMEITSHEGGFLPVLADISTVAKPGQVNQVVVKINNELNETSLPCGA
TKILNNGRKLAKPYFDFFNYSGLQRSVWVIALPEESVKDYSVDYELCGTD
ALVKYEVVTTGEHPVIVRLLDAEGELVAETEGKEGILQVANARLWEVRNA
YLYQIVILITDGNGVLDEYREKIGIRTVRIEGTKILLNDRPVYLKGFGKH
EDFPILGRGFHWGIVKRDFECLKWTNANCFRTSHYPYAEEWYQFADEEGF
LIIDEVPAVGMMRALTVPELLKSHIADTEEMITRDKNHPSVIAWSLFNEP
ETITDYAYEYFKEVFAAAETYDFQSRPMTGAFEKNSKPELCKCYPLCDFI
CLNRYYGWYISGGPEIEEAEELFRDEMDRWKAKELNVPFVFTEFGTDTMA
GLHKLPSIMWSEEYQKEYLEMNFRVFDSYEFVQGELAWNFADFQTTEGIM
RVDGNHKGVFTRDRQPKAAAVVFKDRWE
3D structure
PDB6jz3 Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes.
ChainB
Resolution1.502 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.31: beta-glucuronidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CN0 B D167 H335 N417 E418 Y478 E512 W557 R570 N574 K576 D166 H334 N398 E399 Y459 E493 W538 R551 N555 K557
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565 beta-galactosidase activity
GO:0004566 beta-glucuronidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6jz3, PDBe:6jz3, PDBj:6jz3
PDBsum6jz3
PubMed32105467
UniProtQ6W7J7

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