Structure of PDB 6jma Chain B

Receptor sequence
>6jmaB (length=82) Species: 8355 (Xenopus laevis) [Search protein sequence]
VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAV
TYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
3D structure
PDB6jma Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
ChainB
Resolution6.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R23 P32 R36 R45 K77 R3 P12 R16 R25 K57
BS02 dna B R35 R45 I46 S47 R78 K79 T80 R15 R25 I26 S27 R58 K59 T60
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:6jma, PDBe:6jma, PDBj:6jma
PDBsum6jma
PubMed30923167
UniProtP62799|H4_XENLA Histone H4

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