Structure of PDB 6jil Chain B

Receptor sequence
>6jilB (length=298) Species: 1914 (Streptomyces lavendulae) [Search protein sequence]
MGILALVTDAVSLPIDYDMPPLLEACRTVGITAEVCDWEDGTVDWSRFEA
VVFRSPWTWAERQAEFLAFCERVSHVTRLITPMPLVRWALDKRYLADLAA
HGVPVIPTTVVAPGSDALAAVRDFLAARPEAREFVVKPTDGCYSKDVQRY
QRSLAEPASRHVARLLANGSHVILQPYVESVDRHGETDLTFFDGVYSHAI
HKGAMLMPDGTVHVPTLDFRQARDADEDQRAVAAAALAASVAHLGLDLPL
VCGRVDLVRGADGSPMVLEMELCEPSLNLTFSEDGALRFAQALAERLK
3D structure
PDB6jil Cyclization mechanism catalyzed by an ATP-grasp enzyme essential for d-cycloserine biosynthesis.
ChainB
Resolution2.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.3.5: O-ureido-D-serine cyclo-ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B K92 V135 K137 C142 Y143 S144 Q175 Y177 V178 V181 E186 M205 L206 L268 E269 K92 V135 K137 C142 Y143 S144 Q175 Y177 V178 V181 E186 M205 L206 L268 E269
BS02 MG B E269 E271 E269 E271
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016882 cyclo-ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6jil, PDBe:6jil, PDBj:6jil
PDBsum6jil
PubMed31793174
UniProtD2Z030|DCSG_STRLA Cycloserine biosynthesis protein DcsG (Gene Name=dcsG)

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