Structure of PDB 6j6x Chain B

Receptor sequence
>6j6xB (length=298) Species: 9606 (Homo sapiens) [Search protein sequence]
PDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLH
RMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVI
DVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINV
EKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDL
LGWWLCERQLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETG
GFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVN
3D structure
PDB6j6x Crystal structure of apo GGTaseIII
ChainB
Resolution2.962 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.60: protein geranylgeranyltransferase type II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B E318 V319 E292 V293
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004659 prenyltransferase activity
GO:0004661 protein geranylgeranyltransferase activity
GO:0004663 Rab geranylgeranyltransferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008318 protein prenyltransferase activity
GO:0031267 small GTPase binding
GO:0046872 metal ion binding
Biological Process
GO:0007601 visual perception
GO:0018344 protein geranylgeranylation
GO:0036211 protein modification process
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005968 Rab-protein geranylgeranyltransferase complex

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Cellular Component
External links
PDB RCSB:6j6x, PDBe:6j6x, PDBj:6j6x
PDBsum6j6x
PubMed
UniProtP53611|PGTB2_HUMAN Geranylgeranyl transferase type-2 subunit beta (Gene Name=RABGGTB)

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