Structure of PDB 6iyf Chain B

Receptor sequence
>6iyfB (length=179) Species: 9823 (Sus scrofa) [Search protein sequence]
ANFNVAHGLAWSYYIGYLRLILPGLRARIQAYNQRHKNVLGGIGNHRLHI
LFPLDCGVPDDLSVADPNIRFLHELPQQSADRRVYTNSIYELLENGQPAG
VCVLEYATPLQTLFAMSQDGFSREDRLEQAKLFCRTLEDILADAPEAQNN
CRLIVYQEPTGGSFSLSQEILRHLRQEER
3D structure
PDB6iyf Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins.
ChainB
Resolution1.764 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2BA B Y163 Y167 R238 Y240 Y13 Y17 R83 Y85 MOAD: Kd~6uM
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0032481 positive regulation of type I interferon production

View graph for
Biological Process
External links
PDB RCSB:6iyf, PDBe:6iyf, PDBj:6iyf
PDBsum6iyf
PubMed31167783
UniProtB8XX90|STING_PIG Stimulator of interferon genes protein (Gene Name=STING1)

[Back to BioLiP]