Structure of PDB 6iui Chain B

Receptor sequence
>6iuiB (length=113) Species: 10116 (Rattus norvegicus) [Search protein sequence]
STEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFP
KRPALEPVRSSLRLLNASAYRLQSECRKTVPPEPVDFQLLTQQVIQCAYD
IAKAAKQLVTITT
3D structure
PDB6iui Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics.
ChainB
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B L669 A672 Q673 Q740 Q744 I747 Q748 Y751 K755 K758 L20 A23 Q24 Q88 Q92 I95 Q96 Y99 K103 K106
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
Biological Process
GO:0007420 brain development
GO:0032012 regulation of ARF protein signal transduction

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6iui, PDBe:6iui, PDBj:6iui
PDBsum6iui
PubMed30737283
UniProtQ9Z272|GIT1_RAT ARF GTPase-activating protein GIT1 (Gene Name=Git1)

[Back to BioLiP]