Structure of PDB 6itk Chain B

Receptor sequence
>6itkB (length=318) Species: 196627 (Corynebacterium glutamicum ATCC 13032) [Search protein sequence]
STKKVTVTGAAGQISYSLLWRIANGEVFGTDTPVELKLLEIPQALGGAEG
VAMELLDSAFPLLRNITITADANEAFDGANAAFLVGAKPERADLLANNGK
IFGPQGKAINDNAADDIRVLVVGNPANTNALIASAAAPDVPASRFNAMMR
LDHNRAISQLATKLGRGSAEFNNIVVWGNHSATQFPDITYATVGGEKVTD
LVDHDWYVEEFIPRVANRGAEIIEVRGKSSAASAASSAIDHMRDWVQGTE
AWSSAAIPSTGAYGIPEGIFVGLPTVSRNGEWEIVEGLEISDFQRARIDA
NAQELQAEREAVRDLLLE
3D structure
PDB6itk Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.37: malate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G16 G19 Q20 I21 E47 I48 V92 G93 A94 P96 I113 V134 N136 M160 H192 A246 G9 G12 Q13 I14 E40 I41 V85 G86 A87 P89 I101 V122 N124 M148 H180 A234
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016615 malate dehydrogenase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0030060 L-malate dehydrogenase (NAD+) activity
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0006107 oxaloacetate metabolic process
GO:0006108 malate metabolic process
GO:0006734 NADH metabolic process
GO:0019752 carboxylic acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6itk, PDBe:6itk, PDBj:6itk
PDBsum6itk
PubMed32327663
UniProtQ8NN33|MDH_CORGL Malate dehydrogenase (Gene Name=mdh)

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