Structure of PDB 6ipu Chain B

Receptor sequence
>6ipuB (length=82) Species: 9606 (Homo sapiens) [Search protein sequence]
VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAV
TYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
3D structure
PDB6ipu PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
ChainB
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B T30 R36 R45 T10 R16 R25
BS02 dna B R23 R35 R45 I46 S47 G48 R78 K79 T80 R3 R15 R25 I26 S27 G28 R58 K59 T60
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:6ipu, PDBe:6ipu, PDBj:6ipu
PDBsum6ipu
PubMed31848352
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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