Structure of PDB 6imj Chain B

Receptor sequence
>6imjB (length=411) Species: 10497 (African swine fever virus) [Search protein sequence]
MLNQFPGQYSNNIFCFPPIESETKSGKKASWIICVQVVQHNTIIPITDEM
FSTDVKDAVAEIFTKFFVEEGAVRISKMTRVTEGKNLGKKNATTVVHQAF
KDALSKYNRHARQKRRGMIPPMLVKYFNIIPKTFFEEETDPIVQRKRNGV
RAVACQQGDGCILLYSRTEKEFLGLDNIKKELKQLYLFIDVRVYLDGELY
LHRKPLQWIAGQANAKSSELHFYVFDCFWSDQLQMPSNKRQQLLTNIFKQ
KEDLTFIHQVENFSVKNVDEALRLKAQFIKEGYEGAIVRNANGPYEPGYN
NYHSAHLAKLKPLLDAEFILVDYTQGKKGKDLGAILWVCELPNKKRFVVT
PKHLTYADRYALFQKLTPALFKKHLYGKELTVEYAELSPTGIPLQARAVG
FREPINVLEII
3D structure
PDB6imj Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues.
ChainB
Resolution2.554 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B W31 K89 N91 K106 R109 H110 K185 W31 K89 N91 K106 R109 H110 K180
BS02 dna B R74 K85 N86 K89 S105 R74 K85 N86 K89 S105
BS03 ATP B L128 V129 Q149 R150 K151 R152 R156 E203 F232 I294 R296 K316 L123 V124 Q144 R145 K146 R147 R151 E198 F225 I287 R289 K309
Gene Ontology
Molecular Function
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0051301 cell division
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6imj, PDBe:6imj, PDBj:6imj
PDBsum6imj
PubMed30674878
UniProtP35970|DNLI_ASFB7 DNA ligase (Gene Name=LIG)

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