Structure of PDB 6ih7 Chain B

Receptor sequence
>6ih7B (length=237) Species: 345073 (Vibrio cholerae O395) [Search protein sequence]
SLDFDFTMAFQPIVNCRTKEIFGYEALVRGLNNESAYSVISRVNEDNRYL
FDQMCRVKAIALAAKLGLTSKLSINFLPNAIYVPERCIRTTLEAAKRYQF
PIENIMFEFTEAERVEDVNHIKRIVEYYKSLGFQTAIDDFGSGYSGLNLL
ADFQTNIVKVDMGLIRNIHADQVRQSIMKNCLKLFSDLNIQPLAEGVESH
AEFAWLKAAGVELMQGYYFAKPGFESLPSVNPEFSEA
3D structure
PDB6ih7 Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication.
ChainB
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.52: cyclic-guanylate-specific phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4BW B Q31 L47 V48 R49 A56 I60 C75 N95 M182 G216 V217 E218 G236 Y237 Q11 L27 V28 R29 A36 I40 C55 N75 M162 G196 V197 E198 G216 Y217
BS02 CA B E45 N95 E128 D158 E25 N75 E108 D138
BS03 CA B D158 D159 E215 D138 D139 E195
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6ih7, PDBe:6ih7, PDBj:6ih7
PDBsum6ih7
PubMed31647518
UniProtA0A0H3AJ04

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