Structure of PDB 6i7g Chain B

Receptor sequence
>6i7gB (length=340) Species: 9606 (Homo sapiens) [Search protein sequence]
SLEARAALNQALEMKRQGKREKAQKLFMHALKMDPDFVDALTEFGIFSEE
DKDIIQADYLYTRALTISPYHEKALVNRDRTLPLVEEIDQRYFSIIDSKV
KKVMSIPKGNSALRRVMEETYYHHIYHTVAIEGNTLTLSEIRHILETRYA
VPGKSLEEQNEVIGMHAAMKYINTTLVSRIGSVTISDVLEIHRRVLGYVD
PVEAGRFRTTQVLVGHHIPPHPQDVEKQMQEFVQWLNSEEAMNLHPVEFA
ALAHYKLVYIHPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSDYYHV
LEAANEGDVRPFIRFIAKCTETTLDTLLFATTEYSVALPE
3D structure
PDB6i7g An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.108: protein adenylyltransferase.
3.1.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B E234 V316 H319 V360 G368 N369 G370 R371 Y399 Y400 N407 E132 V214 H217 V258 G266 N267 G268 R269 Y297 Y298 N305
External links
PDB RCSB:6i7g, PDBe:6i7g, PDBj:6i7g
PDBsum6i7g
PubMed31531998
UniProtQ9BVA6|FICD_HUMAN Protein adenylyltransferase FICD (Gene Name=FICD)

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