Structure of PDB 6i4g Chain B

Receptor sequence
>6i4gB (length=356) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
VQALVVDNGSGNVKAGVAGDDAPRSVFPSIVGRPKDAFVGDEAQTKRGLT
LKYPIEQGIVTNWDDMEKIWHHTFYNELRAAPEEHPVLLTEAPLNPKGNR
ERMTQIMFESFNVPAMYVAIQAVLSLYSSGRTTGIVLDSGDGVSHTVPIY
EGYALPHAIMRLDLAGRDLTEYLMKILHERGYGFSTSAEKEIVRDIKEKL
CYIALNFDEEMKTSEQSSDIEKSYELPDGNIITVGNERFRCPEALFQPSF
LGKEAAGIHTTTFNSIKKCDVDIRKDLYGNIVLSGGTTMYEGIGERLTRD
ITTLAPSTMKIKVVAPPERKYSVWIGGSILSSLSTFQQMWITKEEYDESG
PSIVHR
3D structure
PDB6i4g Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B G14 S15 G16 K19 G157 D158 G159 V160 G183 R211 K214 E215 G303 T304 M306 Y307 K337 G9 S10 G11 K14 G140 D141 G142 V143 G166 R194 K197 E198 G286 T287 M289 Y290 K320
BS02 K B D155 S156 G157 V160 S161 D138 S139 G140 V143 S144
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0007010 cytoskeleton organization
GO:0009665 plastid inheritance
GO:0020014 schizogony
GO:0070360 symbiont-mediated actin polymerization-dependent cell-to-cell migration in host
GO:0085017 entry into host cell by a symbiont-containing vacuole
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6i4g, PDBe:6i4g, PDBj:6i4g
PDBsum6i4g
PubMed31199804
UniProtQ8I4X0|ACT1_PLAF7 Actin-1 (Gene Name=ACT1)

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