Structure of PDB 6i2k Chain B

Receptor sequence
>6i2kB (length=245) Species: 39054 (Enterovirus A71) [Search protein sequence]
SDRVAQLTIGNSTITTQEAANIIVGYGEWPSYCSDDDATAVDKPTRPDVS
VNRFYTLDTKLWEKSSKGWYWKFPDVLTETGVFGQNAQFHYLYRSGFCIH
VQCNASKFHQGALLVAILPEYVIGTVAGGTGTEDSHPPYIQTQPGADGFE
LQHPYVLDAGIPISQLTVCPHQWINLRTNNCATIIVPYMNTLPFDSALNH
CNFGLLVVPISPLDFDQGATPVIPITITLAPMCSEFAGLRQAVTQ
3D structure
PDB6i2k Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2.
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN B E72 S74 E63 S65
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6i2k, PDBe:6i2k, PDBj:6i2k
PDBsum6i2k
PubMed30531980
UniProtQ66479|POLG_HE71M Genome polyprotein

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