Structure of PDB 6i1n Chain B

Receptor sequence
>6i1nB (length=271) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDG
VIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSV
ENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTY
DVIIVDSSDNQNFYEKIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKK
LFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLESKEFADLKYY
NYENHSAAFKLPAFLLKEIEN
3D structure
PDB6i1n Plasmodium falciparum spermidine synthase in complex with N-(3-aminopropyl)-trans-cyclohexane-1,4-diamine
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.16: spermidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JFQ B Q93 G124 E147 I148 D178 A179 Q53 G84 E107 I108 D138 A139
BS02 JFQ B Q93 Y102 H103 D127 D196 Q229 Y264 Q53 Y62 H63 D87 D156 Q180 Y215
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004766 spermidine synthase activity
GO:0016740 transferase activity
Biological Process
GO:0006596 polyamine biosynthetic process
GO:0008295 spermidine biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6i1n, PDBe:6i1n, PDBj:6i1n
PDBsum6i1n
PubMed
UniProtQ8II73

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