Structure of PDB 6hyy Chain B

Receptor sequence
>6hyyB (length=217) Species: 9606 (Homo sapiens) [Search protein sequence]
SELRKLFYSADAVCFDVDSTVIREEGIDELAKICGVEDAVSEMTRRAMGG
AVPFKAALTERLALIQPSREQVQRLIAEQPPHLTPGIRELVSRLQERNVQ
VFLISGGFRSIVEHVASKLNIPATNVFANRLKFYFNGEYAGFDETQPTAE
SGGKGKVIKLLKEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNVIRQQ
VKDNAKWYITDFVELLG
3D structure
PDB6hyy Crystal structures and snapshots along the reaction pathway of human phosphoserine phosphatase.
ChainB
Resolution1.566 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.3.3: phosphoserine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D20 D22 D179 D16 D18 D175
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0036424 L-phosphoserine phosphatase activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process
GO:0009612 response to mechanical stimulus
GO:0031667 response to nutrient levels
GO:0033574 response to testosterone
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6hyy, PDBe:6hyy, PDBj:6hyy
PDBsum6hyy
PubMed31205021
UniProtP78330|SERB_HUMAN Phosphoserine phosphatase (Gene Name=PSPH)

[Back to BioLiP]