Structure of PDB 6hy1 Chain B

Receptor sequence
>6hy1B (length=280) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDG
VIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSV
ENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTY
DVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTI
KNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLES
KEFADLKYYNYENHSAAFKLPAFLLKEIEN
3D structure
PDB6hy1 Plasmodium falciparum spermidine synthase in complex with 5'-methylthioadenosine and N,N'-Bis(3-aminopropyl)-1,4-cyclohexanediamine after catalysis in crystal
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.16: spermidine synthase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GXQ B Q93 Y102 H103 D127 D196 S197 D199 E231 Y264 I269 Q53 Y62 H63 D87 D156 S157 D159 E191 Y224 I229
BS02 MTA B G124 G125 D127 E147 I148 V152 D178 A179 S198 P203 A204 L207 G84 G85 D87 E107 I108 V112 D138 A139 S158 P163 A164 L167
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:6hy1, PDBe:6hy1, PDBj:6hy1
PDBsum6hy1
PubMed
UniProtQ8II73

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