Structure of PDB 6hxs Chain B

Receptor sequence
>6hxsB (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
SMGWAAAREAAGRDMLAADLRCSLFASALQSYKRDSVLRPFPASYARGDC
KDFEALLADASKLPNLKELLQSSGDNHKRAWDLVSWILSSKVLTIHSAGK
AEFEKIQKLTGAPHTPVPAPDFLFEIEYFDPANAKFYETKGERDLIYAFH
GSRLENFHSIIHNGLHCGTYLTSDLSLALIYSPHGHGWQHSLLGPILSCV
AVCEVIDHPDPPKYFVVTNNQLLRVKYLLVYSQK
3D structure
PDB6hxs Human PARP16 (ARTD15) IN COMPLEX WITH CARBA-NAD
ChainB
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CNA B H152 G153 S154 S161 I162 L167 H168 Y182 Y193 Y254 H150 G151 S152 S159 I160 L165 H166 Y170 Y181 Y214
Gene Ontology
Molecular Function
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:6hxs, PDBe:6hxs, PDBj:6hxs
PDBsum6hxs
PubMed
UniProtQ8N5Y8|PAR16_HUMAN Protein mono-ADP-ribosyltransferase PARP16 (Gene Name=PARP16)

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