Structure of PDB 6htu Chain B

Receptor sequence
>6htuB (length=76) Species: 9606 (Homo sapiens) [Search protein sequence]
HMNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEG
EGKSKKISKKNAAIAVLEELKKLPPL
3D structure
PDB6htu The crystal structure of Staufen1 in complex with a physiological RNA sheds light on substrate selectivity.
ChainB
Resolution2.888 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B S184 S187 F190 K238 S5 S8 F11 K59 PDBbind-CN: Kd=14nM
BS02 rna B M181 E191 L194 F216 K232 S233 K234 M2 E12 L15 F37 K53 S54 K55 PDBbind-CN: Kd=14nM
External links
PDB RCSB:6htu, PDBe:6htu, PDBj:6htu
PDBsum6htu
PubMed30456389
UniProtO95793|STAU1_HUMAN Double-stranded RNA-binding protein Staufen homolog 1 (Gene Name=STAU1)

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