Structure of PDB 6hro Chain B

Receptor sequence
>6hroB (length=130) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
EAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQ
DGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTC
HILGPDCCIEPADWTKNITDKIDQIIHDFV
3D structure
PDB6hro Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library.
ChainB
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GKZ B M548 L554 M47 L53 MOAD: ic50=0.05uM
PDBbind-CN: -logKd/Ki=7.30,IC50=0.05uM
BS02 GKZ B L515 Y517 D522 M548 L14 Y16 D21 M47 MOAD: ic50=0.05uM
PDBbind-CN: -logKd/Ki=7.30,IC50=0.05uM
External links
PDB RCSB:6hro, PDBe:6hro, PDBj:6hro
PDBsum6hro
PubMed30785281
UniProtQ05320|VGP_EBOZM Envelope glycoprotein (Gene Name=GP)

[Back to BioLiP]