Structure of PDB 6hnv Chain B

Receptor sequence
>6hnvB (length=467) Species: 5476 (Candida albicans) [Search protein sequence]
SDPTHLISKRAAGRTSVSDKPPANFKPHEKPLALSYGMPNHGFFPIDSID
VNLVDYPFQKITPQSTVHISRHTTDPKLIDLARGLQYAAVEGHAPLLQFA
RDFIIRTHKPNYDDWNVFITTGASDGLNKAADVFLDDGDVILVEEFTFSP
FLRFSDNAGAKAVPVKINFDNDSDGIDLTQFVDLLENWEKHYPNLPKPKA
LYTIATGQNPTGFTQSLEFRKKIYDLAVKYDFAIIEDDPYGYLTLPKYEK
PNLEIDDYLKNHLTPSYLELDTTGRVLRVETFSKLFAPGLRLGFIVGHKE
VIDAVKNYSDVVNRGASGLTQTIVNNVIQENFKGVDGWLEWILKMRLNYS
YRKDLLLYSIFESQAYKKGYVDVIDPKAGMFVTFKINLPKDVDVLQKMKL
LLWKLISYGILVVPGYNMTVDLEFSKDRSNFFRLCYALANNDEEILESGK
RLTDAVYEFFSNGLEFH
3D structure
PDB6hnv Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B G165 A166 S167 F191 N252 D280 P282 Y283 T338 K341 G122 A123 S124 F148 N209 D237 P239 Y240 T281 K284
BS02 UN1 B Y130 R371 Y87 R314
BS03 OOG B Y130 R371 Y87 R314
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0008793 aromatic-amino-acid transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0047536 2-aminoadipate transaminase activity
Biological Process
GO:0000949 aromatic amino acid family catabolic process to alcohol via Ehrlich pathway
GO:0006571 tyrosine biosynthetic process
GO:0008643 carbohydrate transport
GO:0009058 biosynthetic process
GO:0009072 aromatic amino acid metabolic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009074 aromatic amino acid family catabolic process
GO:0009094 L-phenylalanine biosynthetic process
GO:0019477 L-lysine catabolic process
GO:0019878 lysine biosynthetic process via aminoadipic acid
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6hnv, PDBe:6hnv, PDBj:6hnv
PDBsum6hnv
PubMed30742897
UniProtA0A1D8PMC5

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