Structure of PDB 6hip Chain B

Receptor sequence
>6hipB (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
AMGKCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGA
PDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDL
AEQV
3D structure
PDB6hip Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.
ChainB
Resolution1.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B G316 V318 D319 E320 G19 V21 D22 E23
BS02 TRP B E329 K332 L372 F377 E32 K35 L75 F80
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0045292 mRNA cis splicing, via spliceosome

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6hip, PDBe:6hip, PDBj:6hip
PDBsum6hip
PubMed30892606
UniProtQ96I25|SPF45_HUMAN Splicing factor 45 (Gene Name=RBM17)

[Back to BioLiP]