Structure of PDB 6h7j Chain B

Receptor sequence
>6h7jB (length=280) Species: 9103 (Meleagris gallopavo) [Search protein sequence]
AAAKVMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADL
VVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAID
RYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQ
ALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVYLRVYREAKEQI
RKIMKEHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFN
WLGYANSAMNPIIYCRSPDFRKAFKRLLAF
3D structure
PDB6h7j Molecular basis for high-affinity agonist binding in GPCRs.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2CV B C85 L93 C47 L55
BS02 5FW B W117 D121 V122 S211 S215 F306 F307 N329 Y333 W79 D83 V84 S173 S177 F227 F228 N250 Y254
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004935 adrenergic receptor activity
GO:0004940 beta1-adrenergic receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0045823 positive regulation of heart contraction
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:6h7j, PDBe:6h7j, PDBj:6h7j
PDBsum6h7j
PubMed31072904
UniProtP07700|ADRB1_MELGA Beta-1 adrenergic receptor (Gene Name=ADRB1)

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