Structure of PDB 6h4g Chain B

Receptor sequence
>6h4gB (length=272) Species: 185431 (Trypanosoma brucei brucei TREU927) [Search protein sequence]
YVAPYFEKSEDETALILKLLTYNVLFSFLDSRDLMTVAGAMWRVEFKQDD
CIMEAGQTTCDKLYIIQDGKADIIKEGQKVYLKVEGTAVGELALMYQTPR
AATVKVCTPELIAWALDRDTYRHLVMGSAIRRRETYIQFLTNIPFLSGLD
NYEKLQLADALSSDEFEPGDYIIRYGEEGEWLYIILEGSVDVVGRDDDGN
EKHVWEFGKGDHVGELEFLNNHANVADVVAKTHVVTAKLNRRHFEMCLGP
VIDVLKRTSQQPNYEYYQSKLK
3D structure
PDB6h4g Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei: E311A, T318R, V319A mutant
ChainB
Resolution2.14352 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP B M271 I291 Y299 G308 E309 L310 A311 R318 A319 A320 Y370 M53 I73 Y81 G90 E91 L92 A93 R100 A101 A102 Y152
BS02 NOS B V410 V422 F425 V431 G432 L434 E435 V443 A444 N481 Y482 Y484 Y485 V192 V204 F207 V213 G214 L216 E217 V225 A226 N263 Y264 Y266 Y267
Gene Ontology
Molecular Function
GO:0008603 cAMP-dependent protein kinase regulator activity
Biological Process
GO:0001932 regulation of protein phosphorylation
Cellular Component
GO:0005952 cAMP-dependent protein kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6h4g, PDBe:6h4g, PDBj:6h4g
PDBsum6h4g
PubMed38517938
UniProtQ385V6

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