Structure of PDB 6gyt Chain B

Receptor sequence
>6gytB (length=168) Species: 9606 (Homo sapiens) [Search protein sequence]
AGKAFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK
SPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSAVYKYCSK
LSEVFEQEIDPVMQSLGYCCGRKLGELFVECTECGRKMHQICVLHHEIIW
PAGFVCDGCLKKSARTRK
3D structure
PDB6gyt Transcription factor dimerization activates the p300 acetyltransferase.
ChainB
Resolution2.5 Å
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C1163 C1164 H1255 C1258 C119 C120 H139 C142
BS02 ZN B C1247 C1250 C1272 C1275 C131 C134 C156 C159
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6gyt, PDBe:6gyt, PDBj:6gyt
PDBsum6gyt
PubMed30323286
UniProtQ09472|EP300_HUMAN Histone acetyltransferase p300 (Gene Name=EP300)

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