Structure of PDB 6gyp Chain B

Receptor sequence
>6gypB (length=527) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SSKEYLPDLLLFWQNYEYWITNIGLYKTKQRDLTRTPANLDTDTEECMFW
MNYLQKDQSFQLMNFAMENLGALYFGSIGDISELYLRVEQYWDRRADKNH
SVDGKYWDALIWSVFTMCIYYMPVEKLAEIFSVYPLHEYLGSNKRLNWED
GMQLVMCQNFARCSLFQLKQCDFMAHPDIRLVQAYLILATTTFPYDEPLL
ANSLLTQCIHTFKNFHVDDFRPLLNDDPVESIAKVTLGRIFYRLCGCDYL
QSGPRKPIALHTEVSSLNVDVYREENSTEVLYWKIISLDRDLDQYLNKSS
KPPLKTLDAIRRELDIFQYKVDSLEEDFRSNNSRFQKFIALFQISTVSWK
LFKMYLIYYDTADSLLKVIHYSKVIISLIVNNFHAKSEFFNRHPMVMQTI
TRVVSFISFYQIFVESAAVKQLLVDLTELTANLPTIFGSKLDKLVYLTER
LSKLKLLWDKVQLLDSGDSFYHPVFKILQNDIKIIELKNDEMFSLIKGLG
SLVPLNSDFRTIVEEFQSEYNISDILS
3D structure
PDB6gyp Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
ChainB
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MET B F64 Q542 F12 Q479
BS02 PHE B S532 F533 S469 F470
BS03 ASN B D60 S532 D8 S469
BS04 ARG B E56 G530 D531 E4 G467 D468
BS05 THR B E56 D60 E4 D8
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008301 DNA binding, bending
GO:0019237 centromeric DNA binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000921 septin ring assembly
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0051382 kinetochore assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031518 CBF3 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gyp, PDBe:6gyp, PDBj:6gyp
PDBsum6gyp
PubMed30478265
UniProtP40969|CBF3B_YEAST Centromere DNA-binding protein complex CBF3 subunit B (Gene Name=CEP3)

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