Structure of PDB 6gwi Chain B

Receptor sequence
>6gwiB (length=450) Species: 768066 (Halomonas elongata DSM 2581) [Search protein sequence]
MQTQDYQALDRAHHLHPFTDFKALGEEGSRVVTHAEGVYIHDSEGNRILD
GMAGLWCVNLGYGRRELVEAATAQLEQLPYYNTFFKTTHPPAVRLAEKLC
DLAPAHINRVFFTGSGSEANDTVLRMVRRYWALKGQPDKQWIIGRENAYH
GSTLAGMSLGGMAPMHAQGGPCVPGIAHIRQPYWFGEGRDMSPEAFGQTC
AEALEEKILELGEEKVAAFIAEPVQGAGGAIMPPESYWPAVKKVLAKYDI
LLVADEVICGFGRLGEWFGSQHYGLEPDLMPIAKGLSSGYLPIGGVLVGD
RVAETLIEEGGEFFHGFTYSGHPTCAAVALKNLELLEAEGVVDRVRDDLG
PYLAERWASLVDHPIVGEARSLGLMGALELVADKTTGQRFDKSLGAGNLC
RDLCFANGLVMRSVGDTMIISPPLVIRREEIDELVELARRALDETARQLT
3D structure
PDB6gwi Widely applicable background depletion step enables transaminase evolution through solid-phase screening.
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F18 Y149 D255 K284
Catalytic site (residue number reindexed from 1) F18 Y149 D255 K284
Enzyme Commision number 2.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B S115 G116 S117 Y149 H150 G151 E222 D255 V257 I258 K284 S115 G116 S117 Y149 H150 G151 E222 D255 V257 I258 K284
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding

View graph for
Molecular Function
External links
PDB RCSB:6gwi, PDBe:6gwi, PDBj:6gwi
PDBsum6gwi
PubMed31360401
UniProtE1V913

[Back to BioLiP]