Structure of PDB 6gnr Chain B

Receptor sequence
>6gnrB (length=114) Species: 8175 (Sparus aurata) [Search protein sequence]
CPLMVKILDAVKGTPAGSVALKVSQKTADGGWTQIATGVTDATGEIHNLI
TEQQFPAGVYRVEFDTKAYWTNQGSTPFHEVAEVVFDAHPEGHRHYTLAL
LLSPFSYTTTAVVS
3D structure
PDB6gnr Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
ChainB
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6J3 B K15 L17 A108 K6 L8 A99 MOAD: Kd=3.61uM
PDBbind-CN: -logKd/Ki=5.44,Kd=3.61uM
Gene Ontology
Molecular Function
GO:0005179 hormone activity
GO:0070324 thyroid hormone binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0007165 signal transduction
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gnr, PDBe:6gnr, PDBj:6gnr
PDBsum6gnr
PubMed30226982
UniProtQ9PTT3

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