Structure of PDB 6gmh Chain B

Receptor sequence
>6gmhB (length=1132) Species: 9823 (Sus scrofa) [Search protein sequence]
EITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPI
DLQAEAQHASPPRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTY
SAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRD
LCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGE
CRSCLENSSRPTSTIWVSMLARAIGQRIVATLPYIKQEVPIIIVFRALGF
VSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKP
GVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALG
RRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKD
FNLELAIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFAST
LSHLRRLNSPIGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLAL
MAYISVGSQPSPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHK
DPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIV
EKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMT
PDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAM
GKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINS
IVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKGFDQEEVF
EKPTRETCQGMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPTKRDC
STFLRTSETGIVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQK
GTCGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSAN
KGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIF
IGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERD
CQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRN
KTQISLVRMPYACKLLFQELMSMSIAPRMMSV
3D structure
PDB6gmh Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B Q731 R841 H842 F895 K934 K942 P1066 I1069 Q703 R812 H813 F853 K892 K900 P1024 I1027
BS02 dna B G1077 R1078 R1085 G1035 R1036 R1043
BS03 ZN B C1119 C1137 C1140 C1077 C1095 C1098
Gene Ontology
Molecular Function
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0003968 RNA-dependent RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gmh, PDBe:6gmh, PDBj:6gmh
PDBsum6gmh
PubMed30135578
UniProtI3LGP4

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