Structure of PDB 6gjw Chain B

Receptor sequence
>6gjwB (length=78) Species: 9606 (Homo sapiens) [Search protein sequence]
EEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAV
DRWQYGDSAVGRHRKVSPNCRFINGFYL
3D structure
PDB6gjw Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1.
ChainB
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C63 C66 H83 C90 C43 C46 H63 C70
BS02 F2H B R62 C66 H67 S87 P88 N89 R42 C46 H47 S67 P68 N69
External links
PDB RCSB:6gjw, PDBe:6gjw, PDBj:6gjw
PDBsum6gjw
PubMed31011505
UniProtP98170|XIAP_HUMAN E3 ubiquitin-protein ligase XIAP (Gene Name=XIAP)

[Back to BioLiP]