Structure of PDB 6g1p Chain B

Receptor sequence
>6g1pB (length=328) Species: 7897 (Latimeria chalumnae) [Search protein sequence]
MVSLAQVRGALCGALLGDCMGAEFEGSDAVELPDVLEFVRLLEKEKKAGT
LFYTDDTAMTRAVIQSLIAKPDFDEVDMAKRFAEEYKKEPTRGYGAGVVQ
VFKKLLSPKYSDVFQPAREQFDGKGSYGNGGAMRVASIALAYPNIQDVIK
FARRSAQLTHASPLGYNGAILQALAVHFALQGELKRDTFLEQLIGEMERI
EGKLPFCSRLKKIKEFLASSNVPKADIVDELGHGIAALESVPTAIYSFLH
CMESDPDIPDLYNNLQRTIIYSISLGGDTDTIATMAGAIAGAYYGMDQVT
PSWKRSCEAIVETEESAVKLYELYCKQL
3D structure
PDB6g1p (ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition.
ChainB
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.143: poly(ADP-ribose) glycohydrolase.
3.2.2.-
3.5.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B T62 D63 D64 D305 T54 D55 D56 D280
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004649 poly(ADP-ribose) glycohydrolase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0060546 negative regulation of necroptotic process
GO:0140290 peptidyl-serine ADP-deribosylation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

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Cellular Component
External links
PDB RCSB:6g1p, PDBe:6g1p, PDBj:6g1p
PDBsum6g1p
PubMed30472116
UniProtH3BCW1|ADPRS_LATCH ADP-ribosylhydrolase ARH3 (Gene Name=adprs)

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