Structure of PDB 6fw7 Chain B

Receptor sequence
>6fw7B (length=414) Species: 243365 (Chromobacterium violaceum ATCC 12472) [Search protein sequence]
KHSSDICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRSKM
LDGKASIELGAGRYSPQLHPHFQSAMQHYSQKSEVYPFTQLKFKSHVQQK
LKRAMNELSPRLKEHGKESFLQFVSRYQGHDSAVGMIRSMGYDALFLPDI
SAEMAYDIVGKHPEIQSVTDNDANQWFAAETGFAGLIQGIKAKVKAAGAR
FSLGYRLLSVRTDGDGYLLQLAGDDGWKLEHRTRHLILAIPPSAMAGLNV
DFPEAWSGARYGSLPLFKGFLTYGEPWWLDYKLDDQVLIVDNPLRKIYFK
GDKYLFFYTDSEMANYWRGCVAEGEDGYLEQIRTHLASALGIVRERIPQP
LAHVHKYWAHGVEFCRDDHPSALSHRDSGIIACSDAYTEHCGWMEGGLLS
AREASRLLLQRIAA
3D structure
PDB6fw7 A semi-synthetic strategy for derivatization of the violacein natural product scaffold
ChainB
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.4.3.23: 7-chloro-L-tryptophan oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G13 S15 D38 M39 G45 R46 G61 A62 G63 R64 R207 L208 I241 L267 W359 G362 D389 W397 M398 G12 S14 D37 M38 G44 R45 G60 A61 G62 R63 R206 L207 I240 L266 W358 G361 D385 W393 M394
BS02 4FW B R64 H163 Y309 R63 H162 Y308
BS03 MG B G13 S15 G12 S14
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0017000 antibiotic biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6fw7, PDBe:6fw7, PDBj:6fw7
PDBsum6fw7
PubMed
UniProtQ9S3V1|VIOA_CHRVO Flavin-dependent L-tryptophan oxidase VioA (Gene Name=vioA)

[Back to BioLiP]