Structure of PDB 6fuw Chain B

Receptor sequence
>6fuwB (length=370) Species: 9606 (Homo sapiens) [Search protein sequence]
LTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYN
DLVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASS
GEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQS
NMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL
RGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNT
VMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWH
PVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHIL
CSGSNDHTSKFWTRNRPGDK
3D structure
PDB6fuw Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex.
ChainB
Resolution3.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B F43 D44 G45 R47 M48 R49 V52 K117 F153 I156 F3 D4 G5 R7 M8 R9 V12 K77 F113 I116
Gene Ontology
Biological Process
GO:0031124 mRNA 3'-end processing

View graph for
Biological Process
External links
PDB RCSB:6fuw, PDBe:6fuw, PDBj:6fuw
PDBsum6fuw
PubMed29358758
UniProtQ9C0J8|WDR33_HUMAN pre-mRNA 3' end processing protein WDR33 (Gene Name=WDR33)

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