Structure of PDB 6fs8 Chain B

Receptor sequence

>6fs8B (length=185) Species: 1601067 (Influenza B virus (B/Memphis/13/2003))

MAMDTFITRNFQTTIIQKAKNTMAEFSEDPELQPAMLFNICVHLEVCYVI
SDMNFLDEEGKSYTNLRPQYEVIEGMPRTIAWMVQRSLAQEHGIETPKYL
ADLFDYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIFSYNQDYSLS
NESSLDEEGKGRVLSRLTELQAELSLKNLWQVLIG

3D structure

• PDB: 6fs8 Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
• Chain: B
• Resolution: 1.8 Å

Enzymatic activity

• Enzyme Commision number: 3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	E4Z	B	T20 F24 M34 N37 I38 H41 E81 R85 D109 E120 K135	T22 F26 M36 N39 I40 H43 E74 R78 D102 E113 K128
BS02	MN	B	H41 D109 E120 V121	H43 D102 E113 V114
BS03	MN	B	E81 D109	E74 D102

Gene Ontology

Molecular Function

• GO:0003723 RNA binding

Biological Process

• GO:0039694 viral RNA genome replication

External links

• PDB: RCSB:6fs8, PDBe:6fs8, PDBj:6fs8
• PDBsum: 6fs8
• PubMed: 29941893
• UniProt: Q5V8Z9