Structure of PDB 6fo2 Chain B

Receptor sequence
>6fo2B (length=409) Species: 9913 (Bos taurus) [Search protein sequence]
LEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRLAS
SLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFL
LNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHAAAYRNALA
NSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVLKQVAEQF
LNIRGAKAKYHGGEIREQNGDSLVHAALVAESAAIGSAEANAFSVLQHVL
GAGPHVKRGSNATSSLYQAVAKGVHEPFDVSAFNASYSDSGLFGFYTISQ
AASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKAGYLMSVESSEGFL
DEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRKSMAASGN
LGHTPFIDE
3D structure
PDB6fo2 X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
ChainB
Resolution4.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H67 R70 L71 L140 D147
Catalytic site (residue number reindexed from 1) H44 R47 L48 L117 D124
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B E90 L96 S97 V98 T99 T101 F312 E67 L73 S74 V75 T76 T78 F283
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fo2, PDBe:6fo2, PDBj:6fo2
PDBsum6fo2
PubMed29765610
UniProtP23004|QCR2_BOVIN Cytochrome b-c1 complex subunit 2, mitochondrial (Gene Name=UQCRC2)

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