Structure of PDB 6fo0 Chain B

Receptor sequence
>6fo0B (length=414) Species: 9913 (Bos taurus) [Search protein sequence]
QDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRL
ASSLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILME
FLLNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHAAAYRNA
LANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVLKQVAE
QFLNIRLSGAKAKYHGGEIREQNGDSLVHAALVAESAAIGSAEANAFSVL
QHVLGAGPHVKRGSNATSSLYQAVAKGVHEPFDVSAFNASYSDSGLFGFY
TISQAASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKAGYLMSVESS
EGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRKSMA
ASGNLGHTPFIDEL
3D structure
PDB6fo0 X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
ChainB
Resolution4.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H67 R70 L71 L140 D147
Catalytic site (residue number reindexed from 1) H46 R49 L50 L119 D126
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R70 K95 L96 V98 T99 S100 T101 Q276 F312 R49 K74 L75 V77 T78 S79 T80 Q251 F287
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6fo0, PDBe:6fo0, PDBj:6fo0
PDBsum6fo0
PubMed29765610
UniProtP23004|QCR2_BOVIN Cytochrome b-c1 complex subunit 2, mitochondrial (Gene Name=UQCRC2)

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