Structure of PDB 6fhk Chain B

Receptor sequence
>6fhkB (length=378) Species: 9606 (Homo sapiens) [Search protein sequence]
AAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGD
AAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKV
QVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDS
QRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGG
TFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDI
SQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFE
ELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDF
FNGRDLNKSINPDEAVAYGAAVQAAILM
3D structure
PDB6fhk Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release.
ChainB
Resolution1.657 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B T14 Y15 G201 G202 G230 E268 K271 R272 S275 G338 G339 T11 Y12 G198 G199 G227 E265 K268 R269 S272 G335 G336
BS02 PO4 B G12 T13 K71 E175 T204 G9 T10 K68 E172 T201
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0140662 ATP-dependent protein folding chaperone

View graph for
Molecular Function
External links
PDB RCSB:6fhk, PDBe:6fhk, PDBj:6fhk
PDBsum6fhk
PubMed30108182
UniProtP0DMV8|HS71A_HUMAN Heat shock 70 kDa protein 1A (Gene Name=HSPA1A)

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