Structure of PDB 6fbq Chain B

Receptor sequence
>6fbqB (length=81) Species: 9606 (Homo sapiens) [Search protein sequence]
TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
KRQRNRCQYCRYQKCLAMGMKREAVQEERQR
3D structure
PDB6fbq Modulation of RXR-DNA complex assembly by DNA context.
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K145 H146 Y147 R164 Q206 E208 R209 R211 K15 H16 Y17 R34 Q76 E78 R79 R81
BS02 dna B E153 G154 R161 K165 R184 N185 Q188 R191 R209 E23 G24 R31 K35 R54 N55 Q58 R61 R79
BS03 ZN B C135 C138 C152 C155 C5 C8 C22 C25
BS04 ZN B C171 C177 C187 C190 C41 C47 C57 C60
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6fbq, PDBe:6fbq, PDBj:6fbq
PDBsum6fbq
PubMed30476562
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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