Structure of PDB 6f39 Chain B

Receptor sequence
>6f39B (length=280) Species: 9606 (Homo sapiens) [Search protein sequence]
PQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFFDLEPSEGCFY
DYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNE
ENGTIMYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFC
SCRPGYELQEDTHSCQECSSELYTEASGYISSLEYPRSYPPDLRCNYSIR
VERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPD
LDTSSNAVDLLFFTDESGDSRGWKLRYTTE
3D structure
PDB6f39 Structure of the C1r-C1s interaction of the C1 complex of complement activation.
ChainB
Resolution5.801 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.41: complement subcomponent C1r.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B Y21 N23 D57 T101 D102 N105 Y17 N19 D51 T95 D96 N99
BS02 CA B L126 D127 G154 Y155 L119 D120 G147 Y148
BS03 CA B Y197 D226 D236 D273 Y189 D218 D228 D265
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:6f39, PDBe:6f39, PDBj:6f39
PDBsum6f39
PubMed29311313
UniProtP00736|C1R_HUMAN Complement C1r subcomponent (Gene Name=C1R)

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