Structure of PDB 6ezl Chain B

Receptor sequence
>6ezlB (length=392) Species: 353153 (Trypanosoma cruzi strain CL Brener) [Search protein sequence]
CLWNNIAALPADPIFSASLVAKKAPEPKADLIIGAYRDAEGHPYPLNVVR
KAEQRLLELPMSGYAPFIEESLKIAYGDSVARENVVGIQGLSGTGSLSIG
ACFLARVLSRDTPVYISDPTWPNHYAVMAAANLTDLRKYRYYDNAKRCID
FDGLLEDLNGAPEGSIVILHACAHNPTGMDPTHEQWAKILEVFQARRLIP
FFDSAYQGYATGSLDNDAYSIRLFARQGMEMLLAQSYSKNMGLYAERVGV
CSIVTANPKKAPLIKSQLETIVRSQYSTPPAHGARVAYLVLSDPELRAGW
EQELRVMSTRVLEMRQALYDGLKRLGTPGSWEHIIQQVGMFSYLGLTKAQ
CEKLIERRVFVLPSGRANMAGLTKRSVELLVKGIDEVVRTVT
3D structure
PDB6ezl Structure of aspartate aminotransferase from Trypanosoma Cruzi at 2.07 Angstrom resolution
ChainB
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.1: aspartate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B H44 S101 G102 T103 W130 D212 A214 Y215 S245 S247 K248 H42 S92 G93 T94 W121 D203 A205 Y206 S236 S238 K239
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006520 amino acid metabolic process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6ezl, PDBe:6ezl, PDBj:6ezl
PDBsum6ezl
PubMed
UniProtQ4D080

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