Structure of PDB 6esl Chain B

Receptor sequence
>6eslB (length=360) Species: 446 (Legionella pneumophila) [Search protein sequence]
VHEQLQVPQCLAAKITVPHKILAENKEFKIIDVLSSDVETLTILADKVSC
GHFVNVSHKLQQQSAQKLLQGVSKLHKDVYEIKHEEEVNAALKEIVSDNI
WQTLTHMTSYYNRSATKDTGVETANWLKSKFEQMAVEYGRTDTSTFFVKT
GWYKQPSLVTVIGKDIKAPAIVIGAHMDTLDGRMPGAGDDGSGSSSIMEA
ARVILSSKTTFKRPIYFIWYAAEERGLVGSQHVVQHFQEQSIPVKAVVQF
DMTGYRNDANDPTMWVFTDYTDRDLSNYLAKLIDHYIHVPVDYSRCGYGC
SDHASWNEEDIPAAFPCETSFADHNPYIHTSSDKMDLLNLEHMTNFSKLA
VAFAIELASE
3D structure
PDB6esl Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition duringLegionella pneumophilaIntracellular Infection of Amoebas.
ChainB
Resolution1.87 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H194 D207 E241 E242 D269 H347
Catalytic site (residue number reindexed from 1) H176 D189 E223 E224 D251 H329
Enzyme Commision number 3.4.11.10: bacterial leucyl aminopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B D207 E242 D189 E224
BS02 ZN B H194 D207 D269 H176 D189 D251
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008235 metalloexopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6esl, PDBe:6esl, PDBj:6esl
PDBsum6esl
PubMed29666285
UniProtQ5ZRR6

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