Structure of PDB 6emy Chain B

Receptor sequence

>6emyB (length=316) Species: 1351 (Enterococcus faecalis)

MTVCQLYAKQIRHRGNVKHNTKLGRERLMRILEQDRLGSCPIDSVKLSDA
KEWALRMKEKGLSYKTINNDKRSLKAAFYTAIQDDCIRKNPFDFQLSDVL
DDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVILLGTGLRISELCG
LTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNEEVYQA
FQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNK
SHEEALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNFYA
HATFDSARAEMERLAA

3D structure

• PDB: 6emy Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.
• Chain: B
• Resolution: 2.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	B	R108 R111 L143 S144 K146 T147 N150 K188 Y209 R225 T254 K307 Q308 N309 R324 K327 K328 H344 H370 M375	R27 R30 L62 S63 K65 T66 N69 K107 Y128 R144 T173 K226 Q227 N228 R243 K246 K247 H263 H289 M294
BS02	dna	B	R95 V98 K99 N101 T102 R106 N150 R153 K156 A157 Y160 I226 S227 Q249 L251 K264 T340 T342 P343 H344 N372	R14 V17 K18 N20 T21 R25 N69 R72 K75 A76 Y79 I145 S146 Q168 L170 K183 T259 T261 P262 H263 N291
BS03	dna	B	N149 R153 Q176	N68 R72 Q95

Gene Ontology

Molecular Function

• GO:0003677 DNA binding

Biological Process

• GO:0006310 DNA recombination
• GO:0015074 DNA integration

External links

• PDB: RCSB:6emy, PDBe:6emy, PDBj:6emy
• PDBsum: 6emy
• PubMed: 29551265
• UniProt: Q7BP35