Structure of PDB 6eff Chain B

Receptor sequence

>6effB (length=206) Species: 28037 (Streptococcus mitis) [Search protein sequence]

GPGSNDTEAPQVKSGDYVVYRGESFEYYAEITDNSGQVNNVVVRNVELTN
MPYLTPDWLKYSTDNLGQPGNATVENPLRTKLYGNVPLDTVVGIYTRYIV
ATDPANNTTRMIQNPNRDGLERFVLTVKSQNEKYDPADPSVTYVNNLSNL
STSERDAVAAAVRAANPSLPSAAKITVSQNGTVTITYPDRSTDTIPANRV
VKDLQI

3D structure

PDB

6eff Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation.

Chain

Resolution

1.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	B	D244 E246 D271 N272 D344	D6 E8 D33 N34 D103
BS02	CA	B	N372 Y375 D434	N131 Y134 D193

External links

PDB	RCSB:6eff, PDBe:6eff, PDBj:6eff
PDBsum	6eff
PubMed	35585145

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