Structure of PDB 6e7x Chain B

Receptor sequence
>6e7xB (length=363) Species: 10116 (Rattus norvegicus) [Search protein sequence]
PPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSI
ITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSS
MIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQD
FVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLY
CTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPSEFPTGLISVS
YDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQ
SNMLNRYLINVTFEGRDLSFSEDGYQMHPKLVIILLNKERKWERVGKWKD
KSLQMKYYVWPRM
3D structure
PDB6e7x Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
ChainB
Resolution2.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 T97 B P78 Q110 Y175 F176 P177 M207 S208 E236 P47 Q79 Y144 F145 P146 M176 S177 E205 PDBbind-CN: -logKd/Ki=6.76,Kd=175nM
External links
PDB RCSB:6e7x, PDBe:6e7x, PDBj:6e7x
PDBsum6e7x
PubMed
UniProtQ00960|NMDE2_RAT Glutamate receptor ionotropic, NMDA 2B (Gene Name=Grin2b)

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