Structure of PDB 6e4w Chain B

Receptor sequence
>6e4wB (length=159) Species: 10116 (Rattus norvegicus) [Search protein sequence]
PTVFRWTGGGKEVYLSGSFNNWSKLPLTRSQNNFVAILDLPEGEHQYKFF
VDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKAPPILP
PHLLQVILNKSCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKY
VTTLLYKPI
3D structure
PDB6e4w Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK).
ChainB
Resolution3.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HUG B R83 S108 V113 R5 S30 V35
External links
PDB RCSB:6e4w, PDBe:6e4w, PDBj:6e4w
PDBsum6e4w
PubMed30036059
UniProtP80386|AAKB1_RAT 5'-AMP-activated protein kinase subunit beta-1 (Gene Name=Prkab1)

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