Structure of PDB 6e1n Chain B

Receptor sequence
>6e1nB (length=639) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
SEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLD
LIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESI
IYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDF
LYPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFA
SWIAFVMFENTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRW
SSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKA
FGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRD
FKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQLRAFVRSP
NFGYAISFILIINFIAVVVETTLNIEVAEFVFGWIYVLEMALKIYTYGFE
NYWREGANRFDFLVTWVIVIGETAQWIRYLLLARMLRLIRLLMNVQRYRA
FIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETEL
AEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFV
SFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDS
3D structure
PDB6e1n Structural basis for activation of voltage sensor domains in an ion channel TPC1.
ChainB
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D335 D337 N339 E341 D305 D307 N309 E311
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005245 voltage-gated calcium channel activity
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0042802 identical protein binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0006816 calcium ion transport
GO:0009845 seed germination
GO:0010119 regulation of stomatal movement
GO:0019722 calcium-mediated signaling
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0080141 regulation of jasmonic acid biosynthetic process
Cellular Component
GO:0000325 plant-type vacuole
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0034702 monoatomic ion channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6e1n, PDBe:6e1n, PDBj:6e1n
PDBsum6e1n
PubMed30190435
UniProtQ94KI8|TPC1_ARATH Two pore calcium channel protein 1 (Gene Name=TPC1)

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