Structure of PDB 6e0h Chain B

Receptor sequence
>6e0hB (length=586) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
NHHVDYVIRFNYGDIDTPEAIKKFEVLLLELSEVGLQTEVRQLFVFVRAA
SKKKLKRAVYQSRVRDWLYGVRNTEPEPASSAKPQSEAERLLVIYHLITV
PKPRHGEWKNVDAIFPLHDEETNRQCMREWSKKTFLSTEDLDRIRNTFGE
HVGFYFAFLQSYFRFLMFPAAFGFSCWLLLGSFSIIYTVVNCLWCIVFIE
YWKRQEEDLSCRWQTKGVSAVHEKRAEFKPEKEVFPATKRMYRQLLQVPF
ALLAAVALGAIIATCFAIEIFISEVYLKGYLVFIPTILVSALIPTMSAVL
LTVATKLNDYENYETQDAYKVALTQKIFVVNFITSYLPIILTAFVYVPFA
SRIVPYLDVFHSINPDRLRKQVIYFTVTAQIVGFALETIVPFVKQRVFRE
YKEARFLTRVRNEAELEDYDVTDDLREMCIQFGYLALFSPVWPLVPVSFL
INNWVELRSDFFKICVECKRPWPQRADTIGPWLDSLGFLSWVGSITSSAL
VYMFSNGHPTTIRCWALLLTIFFSEHLYLIVRYAVRSALAKLEPPNTRRE
RIERFMMRKRYLDTVLFWMRQRGWKESAEVGLSLIT
3D structure
PDB6e0h Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase.
ChainB
Resolution4.05 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E445 E514 E543 E387 E427 E456
BS02 CA B E445 E514 E543 D547 E387 E427 E456 D460
Gene Ontology
Molecular Function
GO:0005245 voltage-gated calcium channel activity
GO:0005254 chloride channel activity
GO:0017128 phospholipid scramblase activity
Biological Process
GO:0017121 plasma membrane phospholipid scrambling
GO:0034220 monoatomic ion transmembrane transport
GO:0045332 phospholipid translocation
GO:0070588 calcium ion transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0032541 cortical endoplasmic reticulum

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6e0h, PDBe:6e0h, PDBj:6e0h
PDBsum6e0h
PubMed30648972
UniProtQ4WA18

[Back to BioLiP]