Structure of PDB 6dts Chain B

Receptor sequence

>6dtsB (length=378) Species: 243274 (Thermotoga maritima MSB8)

TKLTIWCSEKQVDILQKLGEEFKAKYGIPVEVQYVDFGSIKSKFLTAAPQ
GQGADIIVGAHDWVGELAVNGLIEPIPNFSDLKNFYDTALKAFSYGGKLY
GVPYAMEAVALIYNKDYVDSVPKTMDELIEKAKQIDEEYGGEVRGFIYDV
ANFYFSAPFILGYGGYVFKETPQGLDVTDIGLANEGAVKGAKLIKRMIDE
GVLTPGDNYGTMDSMFKEGLAAMIINGLWAIKSYKDAGINYGVAPIPELE
PGVPAKPFVGVQGFMINAKSPNKVIAMEFLTNFIARKETMYKIYLADPRL
PARKDVLELVKDNPDVVAFTQSASMGTPMPNVPEMAPVWSAMGDALSIII
NGQASVEDALKEAVEKIKAQIEKGSHHH

3D structure

• PDB: 6dts Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics.
• Chain: B
• Resolution: 1.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GLC	B	S12 E13 K14 F41 Y213 R303	S8 E9 K10 F37 Y209 R299
BS02	GLC	B	F41 E111 N156 F159 W233	F37 E107 N152 F155 W229
BS03	GLC	B	D66 W67 N156 Y158 W343	D62 W63 N152 Y154 W339
BS04	GLC	B	K45 W343	K41 W339

Gene Ontology

Molecular Function

• GO:0015144 carbohydrate transmembrane transporter activity
• GO:1901982 maltose binding

Biological Process

• GO:0006511 ubiquitin-dependent protein catabolic process
• GO:0008643 carbohydrate transport
• GO:0015768 maltose transport
• GO:0034219 carbohydrate transmembrane transport
• GO:0042956 maltodextrin transmembrane transport

Cellular Component

• GO:0019773 proteasome core complex, alpha-subunit complex
• GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

External links

• PDB: RCSB:6dts, PDBe:6dts, PDBj:6dts
• PDBsum: 6dts
• PubMed: 30204415
• UniProt: Q9S5Y1