Structure of PDB 6do4 Chain B

Receptor sequence
>6do4B (length=318) Species: 9606 (Homo sapiens) [Search protein sequence]
ACPAERSGHVAVSDGRHMFVWGGYKSFYLPREELWIYNMETGRWKKINTE
GDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRVLQWERIDCQ
GIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWHPRGW
NDHVHILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGGRYRDAR
MNDLHYLNLDTWEWNELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDK
QPLSDAWTYCISKNEWIQFNHPYTEKPRLWHTACASDEGEVIVFGGCANN
LLVHHRAAHSNEILIFSV
3D structure
PDB6do4 Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B H109 K147 Y163 R189 W191 R236 R241 S269 W270 W321 H75 K109 Y125 R148 W150 R195 R200 S228 W229 W280
External links
PDB RCSB:6do4, PDBe:6do4, PDBj:6do4
PDBsum6do4
PubMed30526872
UniProtQ9Y2U9|KLDC2_HUMAN Kelch domain-containing protein 2 (Gene Name=KLHDC2)

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